The Clues to Long Life and Disease Resistance Found in Bats?

 

The Bat Pack, a team of researchers at the Australian Animal Health Laboratory (AAHL) in Geelong, conduct a wide range of research into bats and bat borne viruses, and their potential effects on the human population, as part of the effort to safeguard Australia from exotic and emerging pests and diseases.
Their paper, published today in the journal Science, provides an insight into the evolution of the bat's flight, resistance to viruses, and relatively long life.
The Bat Pack, in collaboration with the Beijing Genome Institute, led a team that sequenced the genomes of two bat species -- the Black Flying Fox, an Australian mega bat, and the David's Myotis, a Chinese micro bat.

"Bats are a natural reservoir for several lethal viruses, such as Hendra, Ebola and SARS, but they often don't succumb to disease from these viruses. They're also the only mammal that can fly, and they live a long time compared to animals similar in size."
Flying is a very energy intensive activity that also produces toxic by-products, and bats have developed some novel genes to deal with the toxins. Some of these genes, including P53, are implicated in the development of cancer or the detection and repair of damaged DNA.

 Bats are amazing creatures. They've been around for at least 65 million years, and in that time have become one of the most abundant and widespread mammals on Earth.